Sickle Cell Anaemia | MCQs
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A. Reduction in oxygen carrying capacity of haemoglobin
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B. Single amino acid substitution in the haemoglobin molecule
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C. Linkage between the polypeptide chains
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D. Viral infections of RNA viruses
Explanation
Sickle cell anemia is caused by a mutation in the gene that codes for the beta-globin chain of hemoglobin,
where valine is substituted for glutamic acid at the sixth position, causing the red blood cells to assume a sickle shape.
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