Cancer Biology | MCQs

Explanation

The true statement about Acute Myeloid Leukemia (AML) among the options provided is More than 20% blasts for diagnosis.

AML is characterized by the proliferation of myeloid precursor cells (blasts) in the bone marrow, typically comprising more than 20% of the nucleated cells.

Explanation

The familial cancer syndrome that exhibits autosomal recessive inheritance among the options listed is "Fanconi's anemia."

It is a rare genetic disorder characterized by bone marrow failure and physical abnormalities.

It is inherited in an autosomal recessive pattern, which means an individual must inherit two copies of the mutated gene (one from each parent) to develop the disorder.

The other syndromes listed—ataxia telangiectasia, Bloom's syndrome, Wilson's tumor, and xeroderma pigmentosa

typically exhibit autosomal recessive or autosomal dominant inheritance patterns