Explanation

Massive proteinuria, typically defined as excreting more than 3.5 grams of protein per day in the urine, is a hallmark feature of nephrotic syndrome.

In this condition, the glomeruli in the kidneys become damaged

Leading to increased permeability to proteins

Resulting in their loss through the urine.

This leads to hypoalbuminemia, edema

Aand other complications associated with nephrotic syndrome.