Which of the following drugs is commonly used to lower HbA1c levels in patients with type 2 diabetes?

Biguanides

Insulin

Glucagon

Sulfonylureas

HbA1c reflects long-term blood glucose levels.

Biguanides, such as Metformin, are commonly used to treat type 2 diabetes to help decrease HbA1c.

HbA1c lowering effect

1. Metformin: Typically reduces HbA1c by 1-2% (11-22 mmol/mol).

2. Sulfonylureas: May reduce HbA1c by 0.5-1.5% (5.5-16.5 mmol/mol).

3. Acarbose: Typically reduces HbA1c by 0.5-1% (5.5-11 mmol/mol).