Which of the following drugs is commonly used to lower HbA1c levels in patients with type 2 diabetes?
Answer: Biguanides
Explanation
HbA1c reflects long-term blood glucose levels.
Biguanides, such as Metformin, are commonly used to treat type 2 diabetes to help decrease HbA1c.
HbA1c lowering effect
1. Metformin: Typically reduces HbA1c by 1-2% (11-22 mmol/mol).
2. Sulfonylureas: May reduce HbA1c by 0.5-1.5% (5.5-16.5 mmol/mol).
3. Acarbose: Typically reduces HbA1c by 0.5-1% (5.5-11 mmol/mol).
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